Filling the void: Grieving and healing during a socially isolating global pandemic

Bone graft expanders: filling the void.

Approximately 500,000 bone graft procedures are performed each year in the United States. The surge in the demand for graft material is largely the result of an increase in the number of spinal fusion procedures being performed. In 2001, only 22,000 bone donors existed worldwide, suggesting a shortage of available allograft in the future. This has led to the growing demand for bone graft substi...

Genotype-phenotype correlations: filling the void.

C lassical Mendelian genetics often conjure the image of a well-defined mutation in the DNA sequence that causes a disruption in gene function and characteristic phenotype. However, Mendelian traits can often behave like complex disease traits. One level of complexity is that even a specific mutation may be associated with a wide spectrum of symptoms, with expression perhaps modified by the eff...

Neuronal nicotinic receptors: filling the void?

EFFORTS DURING THE PAST SEVERAL YEARS have enabled an enhanced level of understanding of urinary bladder physiology and pathophysiology, with continued exploitation of muscarinic receptors as drug targets, and the identification of novel molecular underpinnings of pathways such as C fiber afferents and the vanilloid TrpV1 receptors, the noncholinergic nonadrenergic mechanisms and P2X receptors ...

Establishing a Belgian Nutrition Society (BNS): Filling the Void

Bringing hope and healing to grieving patients with cancer.

Cancer is one of the most feared diseases in the world. The fear of this disease contributes to the grief experienced after the diagnosis. The patient, family members, caregivers, and physicians experience this grief, which has many dimensions and can be extremely complicated. Grief is expressed differently by different cultures, and faith can help in dealing with grief, but no one can escape t...